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Summer 2021 Edition of AGA Clinician’s Companion Now Available!

The Summer 2021 edition of the AGA Clinician’s Companion—the go-to resource for busy clinicians who can’t afford to spend hours sifting through research to find clinical value—is available! The AGA...

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Does DAA Therapy for HCV Infection Increase Survival in Patients Who Have...

In patients who have received successful treatment for HCV-related hepatocellular carcinoma (HCC), eradication of the HCV infection with direct-acting antiviral (DAA) significantly reduces risk of...

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Why Are Patients Cured of HCV Infection Still at Risk for Liver Cancer?

Chronic infection with the hepatitis C virus (HCV) causes epigenetic changes in liver cells that alter gene expression patterns and continue to affect risk for hepatocellular carcinoma (HCC),...

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Review: How Does the Tumor Stroma Contribute to Pancreatic Cancer...

Recently developed approaches for reshaping the pancreatic tumor stroma might be used in treatments for pancreatic cancer, according to a review in the March issue of Gastroenterology. The authors...

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How Could Lamins Protect Against Steatohepatitis?

Lamin A/C acts maintains hepatocyte nuclear shape and protects male mice from steatohepatitis by regulating growth hormone signaling and reducing activity of STAT1, researchers report in the November...

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What is the Best Management Strategy for Patients With NAFLD?

Management of patients with non-alcoholic fatty liver disease (NAFLD) requires combined efforts of general practitioners, hepatologists, and other experts, Herbert Tilg explains in a Mentoring,...

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What are the Most Accurate Non-invasive Techniques for Measuring Liver...

Magnetic resonance elastography (MRE) is more accurate than transient elastography (TE) in identifying liver fibrosis of stage 1 or more, researchers report in the February issue of Gastroenterology,...

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Can Disruption of the Intestinal Epithelial Barrier Contribute to...

Mice with defects in intestinal epithelial permeability develop more severe steatohepatitis when placed on a diet high in saturated fat, fructose, and cholesterol (HFCD) than control mice, and colon...

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Can Blood Levels of Ammonia Predict Risk and Frequency of Hepatic...

Fasting levels of ammonia (NH3) in blood identify patients at risk for complications of overt hepatic encephalopathy (HE), researchers report in the June issue of Clinical Gastroenterology and...

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What is the Best Treatment for Severe Alcoholic Hepatitis?

Corticosteroids, alone or in combination with pentoxifylline or N-acetylcysteine (NAC), reduce short-term mortality in patients with severe alcoholic hepatitis, a meta-analysis shows in the October...

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Video: Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis

Obeticholic acid significantly reduces biochemical features of primary biliary cirrhosis (PBC) in patients with an inadequate response to ursodeoxycholic acid (UDCA) therapy, Gideon M. Hirschfield et...

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Does FibroScan Accurately Assess Liver Fibrosis?

Vibration-controlled transient elastography (VCTE) with FibroScan can provide an accurate assessment of liver fibrosis in patients with chronic viral hepatitis, but operator-related and patient-related...

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Probiotics for Cirrhosis?

A probiotic solution significantly reduced the risk of hospitalization for hepatic encephalopathy and markers of liver disease severity in patients with cirrhosis, researchers report in the December...

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Can Exercise Help Patients with Cirrhosis?

Eight weeks of aerobic exercise training increased peak oxygen uptake by muscle and muscle mass, and reduced fatigue, in patients with cirrhosis, researchers report in the November issue of Clinical...

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What are the Roles for Chemokines in Liver Disease?

Sustained hepatic inflammation contributes to the progression of chronic liver diseases such as hepatitis C and non-alcoholic steatohepatitis. In the September issue of Gastroenterology, Fabio Marra...

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Podcast: How Does Fatty Liver Affect Risk for Cardiovascular Disease?

Modification of risk factors for cardiovascular disease—particularly dyslipidemia—is required to reduce morbidity and mortality in patients with nonalcoholic fatty liver disease (NAFLD). In a...

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How Can We Tell if Patients are Still at Risk for HCC after HCV Therapy?

For patients with chronic Hepatitis C virus infection, high levels of α-fetoprotein after therapy can identify those at risk for hepatocellular carcinoma (HCC), researchers report in the July issue of...

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Does DAA Therapy for HCV Infection Increase Survival in Patients Who Have...

In patients who have received successful treatment for HCV-related hepatocellular carcinoma (HCC), eradication of the HCV infection with direct-acting antiviral (DAA) significantly reduces risk of...

View Article

Image may be NSFW.
Clik here to view.

Why Are Patients Cured of HCV Infection Still at Risk for Liver Cancer?

Chronic infection with the hepatitis C virus (HCV) causes epigenetic changes in liver cells that alter gene expression patterns and continue to affect risk for hepatocellular carcinoma (HCC),...

View Article

Image may be NSFW.
Clik here to view.

Review: How Does the Tumor Stroma Contribute to Pancreatic Cancer...

Recently developed approaches for reshaping the pancreatic tumor stroma might be used in treatments for pancreatic cancer, according to a review in the March issue of Gastroenterology. The authors...

View Article
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